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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
26.06
Human Site:
S73
Identified Species:
44.1
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
S73
D
I
I
D
T
T
G
S
G
D
V
N
T
A
T
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
S73
D
I
I
D
T
T
G
S
G
D
V
N
T
A
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
S73
D
I
I
D
T
T
G
S
G
D
V
N
T
A
T
Rat
Rattus norvegicus
Q64560
1249
138274
S73
D
I
I
D
T
T
G
S
G
D
V
N
T
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
S178
D
I
I
D
T
T
G
S
G
D
V
N
T
C
T
Chicken
Gallus gallus
XP_425591
1248
138209
K97
G
L
S
G
R
T
L
K
I
P
T
N
W
V
N
Frog
Xenopus laevis
NP_001085380
1261
139671
R94
A
I
G
G
L
S
G
R
T
L
K
I
P
T
S
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
G160
I
E
R
Y
D
C
S
G
C
G
D
V
D
M
K
Honey Bee
Apis mellifera
XP_395521
1450
161968
R94
Y
I
I
G
I
T
G
R
K
L
K
V
P
S
N
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
A122
D
V
I
D
C
S
G
A
G
D
V
D
T
S
I
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
G93
G
E
I
T
G
L
T
G
R
K
L
K
I
P
L
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
S94
D
V
I
D
C
T
G
S
G
D
I
D
T
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
S174
D
V
I
D
C
T
G
S
G
D
I
D
T
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
93.3
13.3
13.3
0
N.A.
0
26.6
53.3
6.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
93.3
20
26.6
0
N.A.
0
33.3
86.6
13.3
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
60
N.A.
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
86.6
N.A.
N.A.
93.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
0
0
0
29
0
% A
% Cys:
0
0
0
0
22
8
0
0
8
0
0
0
0
8
0
% C
% Asp:
58
0
0
58
8
0
0
0
0
58
8
22
8
0
0
% D
% Glu:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
8
22
8
0
72
15
58
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
50
72
0
8
0
0
0
8
0
15
8
8
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
8
8
15
8
0
0
15
% K
% Leu:
0
8
0
0
8
8
8
0
0
15
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
43
0
0
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
15
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
8
0
0
15
8
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
15
8
50
0
0
0
0
0
29
8
% S
% Thr:
0
0
0
8
36
65
8
0
8
0
8
0
58
8
43
% T
% Val:
0
22
0
0
0
0
0
0
0
0
43
15
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _